Population Pharmacokinetic Modeling and Dose Optimization of Acetaminophen and its Metabolites Following Intravenous Infusion in Critically ill Adults | SpringerLink
Full article: Analytical methodologies for measuring colistin levels in pharmacokinetic studies
Application of population physiologically based pharmacokinetic modelling to optimize target expression and clearance mechanisms of therapeutic monoclonal antibodies - Reig‐Lopez - 2023 - British Journal of Clinical Pharmacology - Wiley Online Library
Dose optimisation of linezolid in critically ill patients based on a population pharmacokinetic model: A two-centre prospective interventional study - ScienceDirect
Pharmacokinetics-guided optimization of QD394 led to QD394-Me having... | Download Scientific Diagram
Physiologically based pharmacokinetic models for the optimization of antiretroviral therapy: recent progress and future perspective | Future Virology
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension | Journal of Medicinal Chemistry
Lead Optimization - Creative Biolabs
![6‐Substituted Pyrrolo[3,4‐c]pyrazoles: An Improved Class of CDK2 Inhibitors - Brasca - 2007 - ChemMedChem - Wiley Online Library](https://chemistry-europe.onlinelibrary.wiley.com/cms/asset/faec6c12-239b-45ff-87d6-062dfe63dc95/mcontent.jpg "6‐Substituted Pyrrolo[3,4‐c]pyrazoles: An Improved Class of CDK2 Inhibitors - Brasca - 2007 - ChemMedChem - Wiley Online Library")
6‐Substituted Pyrrolo[3,4‐c]pyrazoles: An Improved Class of CDK2 Inhibitors - Brasca - 2007 - ChemMedChem - Wiley Online Library
Meloxicam quantification in rabbit plasma by RP-HPLC: optimization and application to pharmacokinetic study | Future Journal of Pharmaceutical Sciences | Full Text
Integrating the Impact of Lipophilicity on Potency and Pharmacokinetic Parameters Enables the Use of Diverse Chemical Space during Small Molecule Drug Optimization | Journal of Medicinal Chemistry
Optimizing antimicrobial use: challenges, advances and opportunities | Nature Reviews Microbiology
Full article: Statistical Sequential Experimentation: Preliminary Mixed Factorial Design, I-Optimal Mixture Design Then Finally Novel Design Space Expansion for Optimization of Tazarotene Cubosomes
Prediction and Optimization of Pharmacokinetic and Toxicity Properties of the Ligand | SpringerLink
PITB: A high affinity transthyretin aggregation inhibitor with optimal pharmacokinetic properties - ScienceDirect
Characterization and optimization of clove oil-loaded nanomicelles for the possible topical use of bacterial infection-led atopic dermatitis | Beni-Suef University Journal of Basic and Applied Sciences | Full Text
Pharmacokinetics-guided optimization of QD394 led to QD394-Me having... | Download Scientific Diagram
Improving the Accuracy of Predicted Human Pharmacokinetics: Lessons Learned from the AstraZeneca Drug Pipeline Over Two Decades: Trends in Pharmacological Sciences
Optimization of P2Y12 Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties | Journal of Medicinal Chemistry
Diagram of pharmacokinetic/pharmacodynamic (PK/PD) module for... | Download Scientific Diagram
A Fast Parameter Identification Framework for Personalized Pharmacokinetics | Scientific Reports
IJMS | Free Full-Text | Optimization, Characterization and Pharmacokinetic Study of Meso-Tetraphenylporphyrin Metal Complex-Loaded PLGA Nanoparticles
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